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Would you be willing to do a very risky therapy to get younger? Do you consider NAD+ infusions very risky? I don’t know if there’s any clinical evidence to support the following musing, but my initial aversion would be that it could throw some reductase enzymes out of whack, and cause a spike in NA...

It'd be faster for you to just tell me why you feel that a blog, written by someone with no formal research or medical background or training, should be viewed as an authoritative source? It is not authoritative, but at least there is no bias. I believe that you should likely reevaluate this. He's ...

How is a write-up on glomerular pressures in various types of genetically modified rats pertinent to the efficacy of rapamycin as an "anti-aging" drug? Talking about Metformin, Here is the context. One doctor? Ok... how is a write-up on glomerular pressures in various types of genetically modified ...

Not a single source, I linked to "fight aging!" which is a different source. You wouldn't expect "fight aging!" to claim that "Metformin Remains a Poor Choice in the Treatment of Aging" if metformin was good. Why do you feel that a blog, written by someone with no formal research or medical backgro...

doubtingthomas wrote: ↑

Fri Apr 15, 2022 9:14 pm

https://www.sciencedirect.com/topics/ph ... ensive-rat

How is a write-up on glomerular pressures in various types of genetically modified rats pertinent to the efficacy of rapamycin as an "anti-aging" drug?

And "FIGHT AGING!" doesn't recommend it. "Metformin Remains a Poor Choice in the Treatment of Aging" https://www.fightaging.org/archives/2021/09/metformin-remains-a-poor-choice-in-the-treatment-of-aging/ Lol. Hey, if a blog that grew from Longevity Meme, written by a mononymous dude that goes by "R...

for what it's worth, Metformin has shown more promise at increasing life expectancy than Rapamycin. I used to think that, but the same doctor does have some concerns about Metformin when used as an anti-aging drug. There are inevitably a lot of concerns with using any compound that interacts with t...

*puts on apologist hat* The word for ship/boat in Hebrew is feminine. That's interesting. I didn't know that. Are you sure? Do you have an authoritative link in which this is expressed? Hi Shulem, Here's the entry for the word from Pealim (a Hebrew learning site). On the "Biblical" front, I don't k...

But Rapamycin is the most promising anti-aging drug. for what it's worth, Metformin has shown more promise at increasing life expectancy than Rapamycin. When compared with NAD+ and Metformin (as well as Sirtuin , and Resveratrol (who all remembers that "miracle" that all of the research said was a ...

*puts on apologist hat*

The word for ship/boat in Hebrew is feminine.